是目前公认的的一套高等有机化学教材，《高等有机化学：结构与机理(第5版)》可供有机化学、药物化学和生物化学等专业的高年级本科生、研究生以及相关领域的科研人员参考。
Preface
Acknowledgment and Personal Statement
Introduction
Chapter 1 Chemical Bonding and Molecular Structure
Introduction
1.1 Description of Molecular Structure Using Valence Bond Concepts
1.1.1 Hybridization
1.1.2 The Origin of Electron-Electron Repulsion
1.1.3 Electronegativity and Polarity
1.1.4 Electronegativity Equalization
1.1.5 Differential Electronegativity of Carbon Atoms
1.1.6 Polarizability， Hardness， and Softness
1.1.7 Resonance and Conjugation
1.1.8 Hyperconjugation
1.1.9 Covalent and van der Waals Radii of Atoms
1.2 Molecular Orbital Theory and Methods
1.2.1 The Hiickel MO Method
1.2.2 Semiempirical MO Methods
1.2.3 Ab Initio Methods
1.2.4 Pictorial Representation of MOs for Molecules
1.2.5 Qualitative Application of MO Theory to Reactivity： Perturbational MO Theory and Frontier Orbitals
1.2.6 Numerical Application of MO Theory
1.3 Electron Density Functionals
1.4 Representation of Electron Density Distribution
1.4.1 Mulliken Population Analysis
1.4.2 Natural Bond Orbitals and Natural Population Analysis
1.4.3 Atoms in Molecules
1.4.4 Comparison and Interpretation of Atomic Charge Calculations
1.4.5 Electrostatic Potential Surfaces
1.4.6 Relationships between Electron Density and Bond Order
Topic 1.1 The Origin of the Rotational (Torsional) Barrier in Ethane and Other Small Molecules
Topic 1.2 Heteroatom Hyperconjugation (Anomeric Effect) in Acyclic Molecules
Topic 1.3 Bonding in Cyclopropane and Other Small Ring Compounds
Topic 1.4 Representation of Electron Density by the Laplacian Function
Topic 1.5 Application of Density Functional Theory to Chemical Properties and Reactivity
T 1.5.1 DFT Formulation of Chemical Potential， Electronegativity， Hardness and Softness，and Covalent and van der Waal Radii
T 1.5.2 DFT Formulation of Reactivity——The Fukui Function ..
T 1.5.3 DFT Concepts of Substituent Groups Effects
General References
Problems
Chapter 2 Stereoehemistry， Conformation， and Stereoselectivity.. "
Introduction
2.1 Configuration
2.1.1 Configuration at Double Bonds
2.1.2 Configuration of Cyclic Compounds
2.1.3 Configuration at Tetrahedral Atoms
2.1.4 Molecules with Multiple Stereogenic Centers
2.1.5 Other Types of Stereogenic Centers
2.1.6 The Relationship between Chirality and Symmetry
2.1.7 Configuration at Prochiral Centers
2.1.8 Resolution——The Separation of Enantiomers
2.2 Conformation
2.2.1 Conformation of Acyclic Compounds
2.2.2 Conformations of Cyclohexane Derivatives
2.2.3 Conformations of Carbocyclic Rings of Other Sizes
2.3 Molecular Mechanics
2.4 Stereoselective and Stereospecific Reactions
2.4.1 Examples of Stereoselective Reactions
2.4.2 Examples of Stereospecific Reactions
2.5 Enantioselective Reactions
2.5.1 Enantioselective Hydrogenation
2.5.2 Enantioselective Reduction of Ketones
2.5.3 Enantioselective Epoxidation of Allylic Alcohols
2.5.4 Enantioselective Dihydroxylation of Alkenes
2.6 Double Stereodifferentiation： Reinforcing and Competing Stereoselectivity
Chapter 3 Strucral Effects on Stability and Reactivity
Chapter 4 Nucleophilic Substitution
Chapter 5 Polar Addition and Elimination Reactions
Chapter 6 Carbanions and Other Carbon Nucleophiles
Chapter 7 Addition，Condensation and Substitution Reactions of Carbonyl Compounds
Chapter 8 Aromatictity
Chapter 9 Aromatic Substitution
Chapter 10 Concerted Pericyclic Reactions
Chapter 11 Free Radical Reactions
Chapter 12 Photochemistry
References to Problems
Index
The stabilization provided by various functional groups contributes to reducedBDEs for bonds to the stabilized radical center. Computational methods can be usedto assess these effects. The BDE can be calculated by comparing the total energy ofthe dissociated radicals with the reactant. Differences in bond dissociation energiesrelative to methane (ABDE) can be taken as a measure of the stabilizing effect of thesubstituent on the radical. Some computed ABDE values are given in Table 3.19 andcompared with experimental values. As an example of the substituent effect on BDEs,it can be seen that the primary C-H bonds in acetonitrile (12 kcal/mol) and acetone(11 kcal/mol) are significantly weaker than a primary C-H bond in methane. The datashow that both electron-releasing and electron-with&awing functional groups stabilizeradicals. The strong bond-weakening effect of amino substituents is noteworthy, bothin its size and the apparent underestimation of this effect by the computations. A recentreevaluation of the ABDE for amines arrived at a value of 13 + 1 kcal/mol, which isin better agreement with the calculations.102b
书很好！！
整体感觉不错，小孩满意，包装一般
包装完好，物流很快！
边做实验边查看，对工作帮助很大。
准备好好看看
书很好，值得买
终于这本经典教材被引进国内了，相信一定会对国内的有机化学的教学和科研起到推动作用。学习有机化学和药物化学的各位同学需要仔细阅读一下了。
书的内容毋庸置疑，书的质量貌似和我想象中的差远了
书虽然没看，但我相信是经典，有一点建议，能用大纸张印刷吗?书太厚纸张太小，不便于复习！
书籍运输没有破损，运送时间较快，这里肯定一下，和以前买了的第十辑--反应与合成，刚好构成姊妹教材，其内容的详细和外文的深奥或许是摆在我面前的拦路虎，但是，对我来说，强烈的吸引力是占据心中的最大的份量，那些困难自然成了阅读的忽略因素，直到有一天，当我抬起疲惫的头时，也就是自己攻坚胜利的那刻了。希望借助“姊妹花”，看清有机化学这片繁茂复杂的森林。。。
书很厚，但只靠胶粘住，就怕很快会脱胶。内容不多说了，做化学的都懂。
一直很想拥有这本书，终于买到了，很开心，包装好，速度快，物超所值
以前有电子版的看着很累，终于买了纸版的，看着很好。
很经典的教材，但你必须懂基础有机化学而且英语达到一定水平才行
虽然自己的英语阅读还可以，但是遇见了这本书，真心给跪了，但是，它是我前进的动力···
这本书，还用多说么，没有之一，好好看绝对对有机有好处，坚持就是胜利啊 ！！！！！！！
送书速度一般，但书的质量很好，是正版，服务很好，非常满意，书虽然较贵但物有所值，建议购买
刚开始有点吃力，但是过亿段时间还是很好的，不错，书中的英文比较简单易懂，还是可以，不错，最好有一定的基础，
很不错，学习路上不孤单，没人教的孩子，只能买书自学，好书（真的）
CAREY的高等有机化学实是经典之作，值得一看！
大概1000多页，全英文，没有较好英语基础的不推荐看。。。不然还不如买本国内教材呢。当然内容不必说，是经典啊
书挺好，就是包装太烂了，书脊处弄坏了，可快递员还TMD跟我说“没得事”，下次希望不要找这家快递公司送货了，真是受不鸟！！！
师兄指明要买的书，虽然不是做机理研究，但还是希望能作参考
分享一下你的购买心得吧！分享一下你的购买心得吧！
对学习有机挺有帮助的。强烈推荐卡雷高等有机“两件套”！
看专业的书还是原著，翻译的全变味了，这本书有深度，要好好品读！
